Thursday, September 29, 2011

New anti-tumor protein spink6

Recently, Huang Qingshan, life sciences, Fudan University Professor leading the research team found a new anti-tumor protein SPINK6 to be effective in inhibiting tumor cell invasion and metastasis, the results should be used for clinical, is expected to reduce patient's tumor after resection of hepatocellular carcinoma recurrence rate for the second time. &Nbsp; Huang Qingshan describes, SPINK6 is they in research small virus anti-tumor role process in the has no intention of found of, in on its role principle preliminary experimental observation in the found, SPINK6 in cancer organization in the by up of role may has two aspects: a is through effect tumor suppression gene p53, suppression tumor cell malignant hyperplasia; II is through regulation cell of sticky echoed movement ability, suppression tumor cell of infiltration and transfer, turn suppression tumor of recurrence and transfer. SPINK6 than other antitumor protein a remarkable 3 advantages produced by body SPINK6, no toxic to human immune; outside SPINK6 is a secretory protein, not entering inside the cells work; after in vivo experimental studies found, the proteins for multiple hepatocellular is particularly strong inhibitory effects. These advantages genetic engineering drugs to be developed for the treatment of liver cancer are important.   

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